Wednesday, September 12, 2012

Diavit Plus - a Medicine to Cure Diabetes

DIAVIT PLUS – A MEDICINE TO CURE DIABETES
FORMULA:
Each soft gelatin capsule contains:
Alpha Lipoic Acid USPNF: 200 mg
Beta Carotene USP: 3 mg
          (As 30% oily dispersion)
Methylcobalamin         : 1500 mcg
Zinc Oxide I.P.: 24.89 mg
Equivalent to Zinc: 20 mg
Selenious Acid USP: 0.14 mg
Equivalent to Selenium: 70 mcg
Chromic Chloride USP: 0.152 mg
Equivalent to Chromium: 50 mcg
Light Magnesium Oxide I.P.:  66.32 mg
Equivalent to Magnesium: 40 mg
Manganese Sulphate USP: 6.152 mg
Equivalent to Manganese: 2 mg
Cupric Sulphate Pentahydrate USP: 1.96 mg
Equivalent to Copper: 0.5 mg
Dibasic Calcium Phosphate I.P.: 316.23 mg
Colors used in capsule shell:
Carmoisine (C.l. No.14720)
Ponceau 4R (C.l. No.16255)
Titaniun, Dioxide I.P.
Adequate overages of vitamin added.
INTRODUCTION:
Millions of Indians are affected by diabetes each year. Diabetic symptoms can range from weakness and fatigue, to nerve problems, or even circulation problem that can result in blindness or amputation of limbs and eventually death.
The human body possesses a complex set of checks and balances to maintain blood glucose concentrations within a narrow range. Glucose homeostasis also depends on the presence of a wide range of micronutrients. It is also proved that deficiency of certain minerals plays an important role in insulin resistance, carbohydrate intolerance and associated complications due to disturbed metabolism affecting all three substrates.
Practically all the diabetic patients are under diet control and they are under high fiber, low calorie diet which affects the essential vitamins and minerals status.
Diabetics experience abnormally high levels of oxidative free radicals, generating accelerated and advanced glycated end products, thus increasing the risk of cell damage and diabetic vascular complications like neuropathy (one of the earliest neuropathic abnormalities that occur in diabetes is the slowing of nerve conduction velocity) and retinopathy.
The goal of supplementing DIAVIT PLUS in the proper term is to allow diabetic patients to maintain good health.
ALPHA LIPOIC ACID:
Alpha Lipoic acid provided in DIAVIT PLUS is proved to be a one of the most potent antioxidant scavenging free radicals in aqueous and lipid medium hence called "Universal antioxidant". Alpha Lipoic acid reaches tissue composed mainly of fat, such as the nervous system as well as those made mainly of water, such as heart.
The other important properties pertaining to Alpha- Lipoic Acid are:
·     It increases the sugar burning ability of insulin.
·     It decreases insulin resistance.
·     It increases ATP production and
·     It decreases the symptoms of diabetic neuropathy.
lt is always suggested to supplement the antioxidants with trace minerals and vitamins to prevent the deficiency and free radical related complications in diabetes.
MINERALS / VITAMINS:
The trace elements and minerals are essential in the assimilation and utilization of vitamins and other nutrients. They aid in digestion and provide the catalyst for many hormones, enzymes and essential body functions and reactions.
Research suggests that people with diabetes may be low in nutrients including Zinc, Copper, Manganese, Magnesium, Selenium, and Vitamin A.
Adequate amount of provitamin A, Beta Carotene provided in DIAVIT PLUS helps in overcoming the deficiency of vitamin A and acts as an excellent antioxidant. Along with Calcium and Phosphorous it boosts the metabolic activities and reinforce the host defense mechanism along with Alpha Lipoic acid and Zinc by combating inflammation, infection and promoting tissue repair.
Zinc is involved both with insulin synthesis by pancreatic B cells and insulin binding to liver and adipose tissue cells. People with Zinc deficiency may have significantly higher glucose levels and lower insulin levels than similar patients without Zinc deficiency.
Chromium and Magnesium deficiency were thought to play role in the development of insulin resistance. Magnesium levels may also associate with hypoglycemia. Therefore, it is reasonable to add Chromium, Magnesium and Zinc in the supplements like DIAVIT PLUS
Copper, Manganese along with Chromium, Magnesium, and Zinc, help in blood sugar control and also provide support to the pancreas directly or to the cells receiving the sugar.
Selenium is an essential nutritional factor which acts as an antioxidant and may be involved in glucose balance. As many complications associated with diabetes may be related to excess free radical activity, prudence demands that adequate selenium be supplied in the diabetic diet.
Methylcobalmin:
Vitamin B12 is involved in a number of different steps in carbohydrate metabolism, and the incidence of 1312 deficiency was significantly greater in a series of diabetics than in the general population. Vitamin 812 deficiency can contribute to nerve damage in the hands and feet.
Methylcobalamin the co-enzyme form of vitamin B12 is the only form of vitamin B12 which can directly participate in homocysteine metabolism. In addition, converting homocysteine to methionine via methyl B12 it generates an increased supply of SAMe (S-adenosyl methionine), the body's most important methyl donor. The benefits of methyl B12 such as protection from neurotoxicity appear to derive from increased production of SAMe. Methyl B12 has also been reported to be neurotrophic or growth-promoting for nerve cells, a property which may help regenerate central and peripheral nervous tissues damaged in diabetic peripheral neuropathy
Methylcobalamin along with Alpha Lipoic acid and Magnesium helps to pre-empt the most common and dangerous diabetic complication i.e. neuropathy.
DIAVIT PLUS covers the benefits of Alpha Lipoic Acid along with Methylcobalamin, antioxidant, multiminerals thus, bringing about a comprehensive therapy for the management of diabetes by reducing the risk of diabetic complications in Type 1, Type 2 diabetes & IGT.
INDICATIONS:
Supportive therapy in diabetes(Type 1 / Type 2 / IGT)
Oxidative Stress and Tissue Injury.
·     Adjuvant in the CARDIVASCULAR DISEASE MANAGEMENT.
DOSAGE:
One capsules a day or as directed by the Physician.
CONTRA INDICATIONS:
·     In patients known to be hypersensitive to any of its components.
·     There are no reports of contra indication of Alpha Lipoic Acid in pregnancy, but it should be avoided in first trimester of pregnancy.
PACKING:
DIAVIT PLUS Capsules are available in blister pack of 10 Capsules, 3 such packs are packed in a carton with prospectus.

1 comment:

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